Network-based model for Sexually Transmitted Diseases

Chlamydia is the most commonly reported sexually transmitted disease in the United States.  Untreated asymptomatic infections may cause permanent damage to the women’s reproductive system.  Routine screening is recommended for women with risk factors to identify these "silent" infections.

In close collaboration with the Tulane School of Public Health team, we develop and analyze a stochastic and individual-based model to simulate the chlamydia epidemic on dynamic sexual networks, and we evaluate the efficacy of screening high-risk men to control chlamydia prevalence in women. Read more about the "Check It" Program.


The proposed model presents a robust framework for modeling other sexually transmitted diseases spreading in a population with assortative mixing.

          
Left: Chlamydia epidemic spread over a static sexual network. Larger nodes (person) have more neighbors (sexual partners). The infection status of each person is tracked using the Susceptible (Green) - Infectious (Red) - Susceptible (SIS) framework.  Right: Model prediction for the impact of male screening on the prevalence in women under different intervention coverage. Darker region gives a higher Chlamydia prevalence in women.

Collaborators

James Mac Hyman (Tulane University)
Patricia Kissinger (Epidemiology, Tulane)
Asma Azizi (Kennesaw State University) 
Charles Stoecker (Global Health Management and Policy, Tulane)


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